Monkeypox (MPV) yog ib hom kab mob DNA zoonotic ob zaug uas tshwm sim los ntawm tus kab mob orthopoxvirus, ib hom kab mob Orthopoxvirus hauv tsev neeg Poxviridae. Nws yog ib qho ntawm tib neeg orthopoxviruses uas suav nrog variola (VARV), cowpox (CPX), thiab tshuaj tiv thaiv kab mob (VACV). Cov tsos mob ntawm tus kab mob monkeypox zoo ib yam li cov kab mob me me. Txij li thaum tshem tawm cov kab mob me me, mob pox tau dhau los ua tus kab mob orthopoxvirus tseem ceeb tshaj plaws los ua rau muaj teeb meem kev noj qab haus huv rau pej xeem. Feem ntau pom nyob rau hauv nruab nrab thiab sab hnub poob teb chaws Africa nws tsis ntev los no tau tshwm sim nyob rau hauv ntau lwm yam tsis muaj kab mob ntawm lub ntiaj teb no.
Ua raws li los ntawm cov kev paub dhau los thaum muaj teebmeem kev tiv thaiv COVID19, qhov chaw tsim khoom xa tawm cov khoom siv tshiab, cov khoom siv thiab cov thev naus laus zis hauv lub sijhawm nrawm, cov neeg tsim khoom qub no tau raug tso cai rau kev tshawb fawb, kev tsim kho thiab xa cov khoom siv rau qhov tshwm sim no (hauv lub ntiaj teb tsim) kab mob hauv lub sijhawm sau tseg.
Cov Qauv: WHO tam sim no pom zoo rau PCR raws li qhov kev sim tshuaj ntsuam xyuas tau muab nws qhov tseeb thiab rhiab heev. Cov qauv kuaj pom zoo tshaj plaws rau cov kab mob liab yog los ntawm cov kab mob ntawm daim tawv nqaij - lub ru tsev lossis cov kua dej los ntawm vesicles thiab pustules, thiab qhuav crusts.
Swabs yuav tsum raug xa mus rau lub chaw kuaj mob hauv kis kab mob kis thoob ntiaj teb, kuj tseem muaj kev xaiv siv cov xov xwm thauj khoom uas yuav ua rau tsis muaj tus kab mob tam sim no.
Qhov twg ua tau, kev kuaj ntshav biopsy yog ib qho kev xaiv hauv qhov no, cov qauv kuaj mob yuav tsum tau muab cia rau hauv ib lub raj qhuav, tsis muaj menyuam (tsis muaj kab mob kis kab mob) thiab khaws cia txias.
Hauv chav kuaj, kev kuaj mob yog nyob ntawm lub sijhawm tiag tiag ntawm PCR qhov 'qhib' piv txwv li tuaj yeem siv rau feem ntau pom hauv chav kuaj thermocyclers lossis 'kaw' piv txwv li txwv siv rau cov cuab yeej tshwj xeeb raws li muab los ntawm cov chaw tsim khoom.
Serology thiab antigen detection txoj kev yog siv tsawg vim hais tias cov kab mob orthopoxviruses yog serologically cross-reactive, yog li tsis txhob muab cov kab mob liab tshwj xeeb.
Xauj los ntawm no peb cov npe khoom lag luam txhawm rau nrhiav cov tuam txhab ntawm cov khoom siv monkeypox PCR thiab cov tshuaj reagents xws li Recombinant MPXV A29 Protein (lub hom phiaj ntawm tus kab mob liab kab mob tshwj xeeb monoclonal antibody) thiab MPXV L1R protein (ib homolog ntawm Vaccinia virus J1R protein).
Cov txheej txheem sau thiab kuaj cov qauv yuav txawv, thov xyuas kom meej tias koj tau ua raws li cov lus qhia tam sim no uas siv rau koj thaj chaw.